The Panthers beat the Eagles 27-7 Sunday to become the fourth team to beat the Panthers in a game in Lake Paajamas.
It was the second win in three weeks for Panthers quarterback Cam Newton, who threw for 348 yards and three touchdowns and ran for another touchdown.
The Panthers also had a touchdown on a pass from Newton to receiver Jerricho Cotchery.
The Eagles scored the last three points of the fourth quarter.
They had a 13-0 lead when Newton threw a 29-yard touchdown pass to DeSean Jackson.
The first-quarter touchdown was by Jackson with two seconds left in the fourth.
The quarterback was sacked by rookie linebacker Mychal Kendricks, who was flagged for unnecessary roughness.
The second-quarter penalty on Jackson, which was also called on Kendricks after the pass was incomplete, led to a Panthers touchdown.
This was the first game for the Eagles to beat a team from California.
They beat the Los Angeles Rams, 49-6, on Jan. 5, 2011, at Candlestick Park.
The next game was against the San Francisco 49ers, 44-14, in Santa Clara, California.